Canine coat color, surprising genetics

If a purebred dog is born with a coat color that it is not supposed to have, it may be due to hidden genes. Kari Ekenstedt, DVM, Ph.D. who is the assistant professor of anatomy and genetics, along with Dayna Dreger, Ph.D., lead researchers in Ekenstedt’s canine genetics research laboratory studied 212 different dog breeds and found that gene variants caused breeds to have traits that the breed standard did not allow. These included coat color, and other traits. For example, they found that 48 different breeds had the tailless gene variant, such as the Dachshund. Although the variant was low, it is possible that a Dachshund could be born tailless.  

One of the “fault” alleles allows the brown color. This allele produces the chocolate Labrador Retriever, yet the researchers found the same allele in breeds that do not allow the brown color, such as the German Shepherd and Rottweiler.

The lesson learned from this study is that if a puppy is born that is not what the breed standard calls for, it is not necessarily due to “bad” breeding, but the expression of a trait that was hidden and has surfaced.

Hearing loss in dogs

A number of breeds of dogs, mostly those breeds that have the merle, piebald or white coats, are prone to deafness. However, dogs that are subjected to frequent loud noise can suffer from hearing loss the same as people. This is referred to as noise-induced hearing loss.

A study conducted at the University of Illinois at Urbana-Champaign by Dr. Kari Foss, found that working dogs such as police, sniffer and gun dogs are a strong candidate to suffer from hearing loss. According to Foss,

“Most commonly, noise-induced hearing loss results from damage to the hair cells in the cochlea that vibrate in response to sound waves,” Foss said. “However, extreme noise may also damage the eardrum and the small bones within the inner ear, called the ossicles.”

         The most common signs that a dog is losing his ability to hear are when the dog fails to respond to commands, or they sleep through noise that would normally wake them up. They may bark excessively or make unusual sounds. Sometimes a dog may have a hearing loss in one ear only. If that is the situation, the dog may hear sounds but not be able to tell where it came from.  

         The researchers recommended that dogs who must work around loud noise wear hearing protection that is designed for dogs. It is also possible that dogs can lose hearing from ear infections and illnesses and as they age.

         If a potential dog owner is going to purchase a breed where deafness is a problem, they must be sure that the breeder has done a BAER test to determine if the puppy is deaf or not.

Unwanted behavior in dogs – surprising findings

In a study of 14,000 dogs, fully 73% of the dogs studied had unwanted behavior. One-third of the dogs studied had noise sensitivity. The other behaviors included fearfulness of people, other dogs and unfamiliar locations, fear of surfaces and heights, inattention and impulsivity, compulsive behavior, aggressiveness and separation anxiety. The most common were noise sensitivity, fear of surfaces and heights and general fearfulness.  

Professor Hannes Lohi’s research group from the University of Helsinki conducted the study and found that fearfulness and aggressive behavior were linked to each other as well as impulsivity, compulsive behavior and separation anxiety. The researchers also discovered that many unwanted behaviors are inherited. Their hope is that better breeding may help eliminate these behaviors.

Author’s Note: The article states, “The problems appear to be quite breed-specific. For example, in Border Collies we observed more compulsive staring and light/shadow chasing, behaviours that occurred more rarely in all other breeds.” Studies such as this are interesting, however, it should be considered what the breed traits are, the excessive staring could actually be the Border Collie “eye.” Since Border Collies herd livestock, they may have a tendency to chase light and shadows if their instinctive herding needs are not met.

Cat food formula surprise

Different groups of researchers are interested in learning how much wildlife cats kill for food. With this in mind researcher Roland Kays from North Carolina State University and the North Carolina Museum of Natural Sciences decided to study how much wildlife domestic cats kill and eat to supplement the food they are fed by their owners. What they found was very surprising as well as important for cat owners.

The researchers found that they could not determine the amount of wildlife that cats eat because they were studying elements in cat food as a comparison. The reason why this study failed is because cat food manufacturers do not use consistent types and amounts of ingredients in their food. Even foods that were the same flavor and brand were inconsistent. The researchers found that the less expensive brands had more corn products and that the cat food produced in the United Kingdom had a lower amount of corn products.

Author’s Note: This information accounts for why some cats who like a certain brand and flavor of food will suddenly refuse to eat that food. Cats have a very acute sense of smell and they can detect the change in their food. Dog food is no better and dogs can suddenly reject a food that they liked previously. Changing the formula of dog or cat food can also induce loose stools and weight changes in a dog or cat.

Managing aggressive behavior in dogs

Dr. Emma Williams, from the School of Psychological Science at the University of Bristol has conducted a study about managing aggressive dog behavior. According to her research, aggression in dogs is a worldwide problem.

She found that animal behaviorists need to focus on helping dog owners feel confident that the rehabilitation program prescribed will work. Behaviorists must also ensure that the dog owner is capable of initiating and following through with the program. Behaviorists should not only focus on the behavior of the dogs, but also the behavior of the owner when developing a rehabilitation program. They found that when a dog acts badly toward a person or another dog, the dog’s owner may react with extreme negative feelings.

What they also found was that positive reinforcement-based behavior modification techniques were very effective in rehabilitating aggressive dogs while punishment-based methods were detrimental for the dog and led to increased aggression.       

Sue’s note: At the first sign of aggression, even in a puppy, the dog owner must consult with a certified canine behavior consultant. Too often dog owners feel that the dog will out-grow the aggression when in reality it always gets worse if not addressed immediately.

Human breast cancer drug helps dogs with lung cancer

The HER2 gene which is found in women with breast cancer, has been linked with canine pulmonary adenocarcinoma (CPAC) in dogs. Researchers at the Translational Genomics Research Institute (TGen) which is an affiliate of the City of Hope and Ohio State University found that a drug, neratinib, can help the over 40,000 dogs who develop CPAC each year.

CPAC is an aggressive cancer that is similar to the type of human lung cancer that non-smokers develop. This study has given researchers more information about the genetics of this disease and treatment options that can help both dogs and humans.

Raw meat diet in dogs associated with antibiotic-resistant bacteria

No matter what age the dog is, eating a raw meat diet causes them to pass antibiotic resistant Escherichia coli (E.coli) in their feces which can be transmitted to humans.

Researchers from the University of Bristol conducted an in-depth study of 823 dogs of all ages.

They found that dogs who lived in the country had a strong risk factor in passing antibiotic resistant E.coli but dogs who live in the city had more complicated risk factors that may be linked to the variety of lifestyles and exposure to other dogs.

E. coli is found in the intestines of both humans and animals and is a common cause of various diseases including urinary tract infection and can cause sepsis in other parts of the body.

The bottom line is that feeding raw meat to dogs is not safe for both the dog and humans. If a dog owner insists on feeding raw meat to their dog, they must be very careful of infection.

A link between a dog’s sense of smell and vision

Researchers at Cornell University have found that there is a neurological link between a dog’s sense of smell and their vision. This study shows that a dog perceives his environment using both vision and scent. This is the first time that scientists have found a neurological connection of this nature in any animal.

In addition, scientists have found that dogs have connections between areas in the brain that process memory and emotion which are similar to humans but that they also have connections between the spinal cord and the occipital lobe which are not found in humans.

Riley

This finding explains why blind dogs are able to function, being able to play fetch and navigate their surroundings much better than people with similar blindness. That is comforting for people who own dogs who are blind or have gone blind.

Author’s Note: Although blind dogs can find their way around better than people, it is still a good idea to not move furniture around. If you have to move or add furniture, you can put a unique gentle scent on the corners of the furniture at the dog’s level to help the dog locate and identify the new or moved object.

We also have to think about how the relationship between scent and vision affects dogs in terms of training and their reaction to the environment, taking into consideration personality traits such as friendliness, fear, aggression etc. While we know that many of the personality traits of dogs are inherited, is it possible that these findings might explain further exactly how and what is inherited. Many people do not realize how complex dogs and perhaps other animals are.

Male dogs more likely to develop Transmissible Venereal Tumors

Researchers at the University of Cambridge’s Department of Veterinary Medicine discovered that male dogs, especially free roaming dogs, were four to five times likely to develop the Oro-nasal form of Canine Transmissible Venereal Tumors (CTVT) than female dogs.

CTVT is an unusual cancer that can spread between dogs that come in contact. This type of cancer is infectious because the living cancer cells can be physically transplanted from one animal to another. The researchers feel that the reason it is more prevalent in male dogs is because they spend more time sniffing and licking female dog genitalia.

The common symptoms are difficulty breathing, nasal deformation or bloody or other discharge from the nose and/or mouth. Fortunately, this type of cancer is treatable with Vincristine chemotherapy.  

The researchers noted that transmissible cancers are found in Tasmanian Devils as well as marine bivalves such as mussels and clams.

Does a dog owners stress level affect their dog?

According to a study conducted at the Linköping University, Sweden dogs mirror their owners stress level. The study is just the beginning and more research is needed. The dogs in the study were Border Collies and Shetland Sheepdogs owned by woman. The researchers did note that the higher level of stress did not influence the dog’s personality but it did affect the owners. They also took into consideration that the two breeds studied are bred to respond quickly to commands from their owners. Additional studies are planned to

explore other breeds with the goal of being able to match dogs and people more successfully. They want to see if other breeds are not as affected by their owner’s stress level.

Sue’s Note: It is critical that the climate of a household and the people in it are seriously considered when selecting a breed or type of dog to add to the family. Certain breeds are more active than others. It is never a good idea to introduce a highly excitable dog into a very active household. For example, some terriers may not be a good match for a home where there are young, highly active children. Just like people, dogs can reach their tolerance level and if pushed too far may withdraw or bite.