A team from the University of Pennsylvania announced that they have cured X-linked retinitis pigmentosa, a blinding retinal disease in dogs when caught early. XLRP causes gradual vision loss starting at a very young age in dogs, often as early as five weeks. It is an inherited retinal disease.
http://ghr.nlm.nih.gov/condition/retinitis-pigmentosa
Continuing the research the veterinarian researchers found that the gene therapy helped dogs at 12 weeks of age (mid-stage disease) when about 40% of the eye’s photoreceptor cells were dead and then at 26 weeks of age (late-stage) when 50 – 60% of the cells were dead. What the researchers found was that they were able to halt the degeneration of the photoreceptor cells in the treated area.
Now they’ve shown that they can cure the canine disease over the long term, even when the treatment is given after half or more of the affected photoreceptor cells have been destroyed.
To date, dogs have maintained their vision for over two years after treatment. This is very exciting because humans suffer from the same type of blindness. With that in mind, researchers are already examining human patients to determine how to treat their blindness and who might qualify for future treatments.
Again, man’s best friend is offering hope to humans who suffer from this type of cell death that causes blindness. Since this is an inherited disease, breeders should have their dogs examined by a certified canine ophthalmologist and register their dogs with the Canine Eye Registration Foundation, CERF. http://www.tctc.com/~maplerg/cerf-.htm This will help researchers continue to develop cures for blindness as well as prevent the breeding of dogs who have this inherited disease.
Sue’s Note: All pets who are blind can live a happy life. My cat is blind and is happy and safe. It helps if things are not moved around or left out in the open where the blind pet will bump into them. Blind pets should never be allowed outside unless they are in a fenced area or on a leash.
A Blog by Susan Bulanda 