Researchers have found that a gene mutation is responsible for breathing difficulties in Norwich Terries and Bulldogs that is not related to brachycephalic faces. Brachycephalic faces can cause Brachycephalic Obstructive Airway Syndrome or BOAS. Researchers found that Norwich Terriers can suffer from Upper Airway Syndrome or UAS which is similar to BOAS.

The team from the University of Edinburgh’s Royal (Dick) School of Veterinary Studies, led by Jeffrey Schoenebeck found that a mutation of the ADATS3 gene was linked to the breathing problems. This mutation is also found in French and English Bulldogs. The gene has been linked to edema, (swelling and fluid retention) which is a problem with UAS and BOAS causing breathing difficulties.
Once the researchers develop a test to determine which dogs have the gene mutation, breeders can better control breeding practices. What is important to recognize is that the mutation may occur in other breeds as well shedding a whole new light on breathing issues in dogs.