DNA Study shows disease causing variants in cats

Studying the DNA of animals helps breeders produce healthier animals. A recent study conducted by Heidi Anderson from Wisdom panel in the USA and researchers from the University of Helsinki in Finland found that there were 13 genetic variants in pedigree cats that are linked to diseases. This was more than researchers previously thought. The good news is that these variants are decreasing in breeds that are regularly DNA tested.

The researchers studied over 11,000 cats which included 90 pedigree breeds and breed types as well as 617 non-pedigree cats. What is interesting is that the researchers found that there was more genetic diversity in the non-pedigree cats. The non-pedigree cats had three disease associated variants found exclusively in non-pedigree cats. The bad news is that they found 13 disease associated variants in 47 breeds where none had been found previously. In the past, 40% of Persian cats were affected by PKD1, the variant that causes Polycystic Kidney Disease yet of the 118 Persians tested, none had the variant, yet it was found in Main Coon and Scottish Straights cats. Good breeding practices will continue to provide healthier pets for everyone.

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