Myoclonic epilepsy in dogs and Juvenile myoclonic epilepsy in humans share a common gene

Myoclonic epilepsy in dogs is very similar to juvenile myoclonic epilepsy in humans. Veterinarian researchers have identified a specific gene that is linked to this type of epilepsy.


Myoclonic seizures are brief shock-like jerks of either a single muscle or a muscle group. In humans the person is typically awake and can think clearly.

In dogs the seizures usually occur by the time the dog is six months old and when they are resting. It appears that some of the seizures can be triggered by light.

The good news is that researchers have identified a gene that is connected to this form of seizure. The gene, DIRS1 is unique to this type of epilepsy and has not been linked to any neurological disorder before. The good news is that the DIRS1 gene is similar to those found in humans.

Researchers have developed a genetic test for dogs which will help veterinarians and breeders identify dogs who have this gene and enable them to modify breeding programs. It seems that  that the Rhodesian Ridgeback is especially susceptible to this form of epilepsy, but it has been found in many other breeds as well.

While more research is needed to further understand the connection between the gene and epilepsy, it is a breakthrough. Once the role of the gene is understood then researchers can develop a cure or treatment for this form of epilepsy.

Again, veterinarian research has the potential to help humans. Dogs are indeed our best friends.


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